Functional Disruption of Cerebello-thalamo-cortical Networks in Obsessive-Compulsive Disorder
نویسندگان
چکیده
منابع مشابه
Cortical thinning in obsessive compulsive disorder.
Although studies of obsessive-compulsive disorder (OCD) over the last 20 years have suggested abnormalities in frontal-subcortical circuitry, evidences of structural abnormalities in those areas are still imperfect and contradictory. With recent advances in neuroimaging technology, it is now possible to study cortical thickness based on cortical surfaces, which offers a direct quantitative inde...
متن کاملReduced functional connectivity within the limbic cortico-striato-thalamo-cortical loop in unmedicated adults with obsessive-compulsive disorder.
Cortico-striato-thalamo-cortical (CSTC) loops project from the cortex to the striatum, then from the striatum to the thalamus via the globus pallidus, and finally from the thalamus back to the cortex again. These loops have been implicated in Obsessive-Compulsive Disorder (OCD) with particular focus on the limbic CSTC loop, which encompasses the orbitofrontal and anterior cingulate cortices, as...
متن کاملCortico-Striato-Thalamo-Cortical Circuitry, Working Memory, and Obsessive–Compulsive Disorder
Compulsive Disorder. Obsessive–compulsive disorder (OCD) is characterized by persistent anxious thoughts (obsessions) and repeated rituals (compulsion) (1, 2). The symptoms point to dysfunctions in inhibitory control, implicating the dorsal anterior cingulate cortex (dACC) as part of a wider cortico-striato-thalamo-cortical (CSTC) circuitry based on findings from resting-state and task-dependen...
متن کاملFunctional neuroimaging in obsessive-compulsive disorder.
BACKGROUND AND AIM Obsessive-compulsive disorder (OCD) is a severe, highly prevalent and chronically disabling psychiatric disorder that usually emerges during childhood or adolescence. This paper aims to review the literature on functional neuroimaging in OCD, analysing the reported dysfunctional connectivity in the corticostriatothalamocortical circuitry. METHOD This study included papers p...
متن کاملObsessive Compulsive Disorder in Adolescents
Background: Obsessive-compulsive disorder (OCD) is a common psychological disorder with a high rate of incidence reported in adolescents. This disorder causes many social and economic costs for the affected people and the society as well as affecting the social, educational and occupational performance of these adolescents. Method: Some papers on obsessive-compulsive disorder in adolescents in...
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ژورنال
عنوان ژورنال: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
سال: 2020
ISSN: 2451-9022
DOI: 10.1016/j.bpsc.2019.12.002